Summary: According to a significant research, people who are biologically older than they are chronologically older are about 30 % more likely to develop memory. Indicators like heart function and lipid, which are used to determine biological age, show how the body’s systems are aging.
Researchers found that people with older brains even displayed changes like reduced grey problem, which are related to memory. Although the investigation does not establish causality, it suggests that life modifications that slow biological aging may help to lower the risk of dementia.
Important Information:
- 30 % Higher Risk: A substantially higher risk of dementia is associated with advanced biological age.
- Higher natural period was linked to dementia-related white matter loss, according to the findings.
- Life Impact: Diet, exercise, and healthier lifestyle habits may all influence the biological age.
AAN as the cause
According to a study published online on April 30, 2025, in Neurology, persons whose natural period is higher than their chronological age may have memory.  ,
Markers of aging, such as heart function, blood pressure, and cholesterol, are used to determine biological age.
The review only demonstrates an association between superior biological age and memory.
” With the expanding effects of delirium around the world, identifying risk factors and putting in protective measures is essential,” said study author Yacong Bo, PhD, of Zhengzhou University in China.
” We can affect our biological age through life factors like diet and exercise, but none of us can alter our chronological age,” the statement continues.
280, 918 people from a United Kingdom collection who were on average chronological 57 at the start of the research and who didn’t own dementia at the time.
They were followed for a median of 14 times. 4, 770 individuals in that time also developed memory.
To determine biological period, the researchers used two strategies. The methods used to measure other biomarkers in the body, such as regular cell volume and white blood cell depend, in addition to heart function, blood pressure, and cholesterol.
These techniques demonstrate how different body parts, such as digestion, immunity, liver, kidneys, heart, and another systems, interact as we get older.
While those who later developed memory had an average chronological age of 65 at the start of the investigation, compared to 57 for those who maintained no memory, their common biological age was 55, according to one of the techniques, compared to 45 for those who had no memory.
Researchers divided the individuals into four groups based on biological ages, finding that those with the most innovative genetic years were about 30 % more likely than those in the least team to develop memory.
Other variables that might influence the risk of dementia, such as age, schooling, and smoking status, were taken into account in these effects.  ,
Additionally, the researchers discovered that people with advanced biological age even experienced brain changes that are linked to dementia, such as black matter volume loss.
Some of the relationship between innovative biological age and dementia is explained by these mental structure changes, but not all of it, according to Bo.
These findings support the hypothesis that a more sophisticated natural period may be responsible for the development of dementia by causing a significant shift in brain structures.
A drawback of the investigation was that databases individuals were more health conscious than the general population, making them less likely to produce memory.
Henan Province and Zhengzhou City Institutions in China provided funding for the review.
About this study on aging and delirium
Author: Renee Tessman
Source: AAN
Contact: Renee Tessman – AAN
Image: The image is credited to Neuroscience News
Initial research: The results will be published in Neurology.
