Summary: A new AI model, based on the PV-RNN framework, learns to generalize language and actions in a manner similar to toddlers by integrating vision, proprioception, and language instructions. Unlike large language models (LLMs) that rely on vast datasets, this system uses embodied interactions to achieve compositionality while requiring less...
Long COVID Impairs Exercise Capacity and Cognition for Times
Summary: A study of nearly 1,000 people with post-COVID-19 syndrome (PCS) revealed that two-thirds still experienced significant symptoms, including reduced exercise capacity and cognitive performance, two years after infection. Persistent symptom clusters included fatigue, neurocognitive disturbances, and post-exertional malaise, with worse outcomes in individuals with obesity, lower education, or severe...
Decoding the Information: How Taxi Drivers Think Different From AI
Summary: A study reveals that London taxi drivers prioritize complex and distant junctions during their initial “offline thinking” phase when planning routes, rather than sequentially considering streets. This efficient, intuitive strategy leverages spatial awareness and contrasts with AI algorithms, which typically follow step-by-step approaches.The findings highlight the unique planning abilities...
Adults With ADHD May Have Shorter Life
Summary: A study analyzing data from over 30,000 adults with diagnosed ADHD found a reduction in life expectancy of 4.5–9 years for men and 6.5–11 years for women compared to those without ADHD. Researchers caution that the findings may overestimate the reduction due to underdiagnosis and additional health problems among...
Targeting Reward Pathways to Treat Depression
Summary: New research highlights how the brain’s reward-learning system can guide personalized treatments for depression. By studying two brain signals, expected value and prediction error, researchers identified markers that predict recovery potential and tailored responses to rewards and setbacks.This approach goes beyond symptom management, targeting the brain processes driving specific...
Maternal X Chromosome Accelerates Brain Aging
Summary: New research shows that female mice expressing only a maternal X chromosome experience faster brain aging and cognitive decline compared to those expressing both maternal and paternal X chromosomes.The maternal X accelerates aging in the hippocampus, a key region for memory and learning, and silences certain genes essential for...
Dopamine Drives Aggression Learning in Males
Summry: New research reveals that dopamine plays a crucial role in teaching young male mice to fight, with the chemical’s influence diminishing as they gain experience. In novice fighters, boosting dopamine increased aggression, while blocking it stopped them from fighting.However, experienced fighters showed no changes in behavior regardless of dopamine...
Microglia Act Separately in Male and Female Brains
Summary: Microglia, the brain’s immune cells, play vital roles in clearing toxins and maintaining neuronal health but can also contribute to neurodegenerative diseases if overactive. New research reveals sex-based differences in how adult male and female microglia respond to the enzyme inhibitor PLX3397, a common tool in microglial research.While male...
Abnormalities Travel Aging and Shape Epigenetic Clock
Summary: A new study has uncovered a direct link between somatic mutations and epigenetic modifications, challenging established views on aging. Researchers found that random genetic mutations drive predictable changes in DNA methylation, offering new insights into the relationship between mutation accumulation and epigenetic clocks.This suggests that epigenetic changes may track,...
Antibiotics and Another Pharmaceuticals May Lower Dementia Chance
Summary: A study analyzing data from over 130 million individuals found that antibiotics, antivirals, vaccines, and anti-inflammatory medications are associated with a reduced risk of dementia. This supports the idea that infections and inflammation contribute to dementia and highlights the potential of repurposing existing drugs for prevention or treatment.While some...