Summary: Researchers have mapped over 70,000 synaptic connections in rat neurons using a silicon chip with 4,096 microhole electrodes, significantly advancing neuronal recording technology. Unlike traditional electron microscopy, which only visualizes synapses, this method also measures connection strength, providing deeper insight into brain network function.The chip mimics patch-clamp electrodes but...

Summary: A new study reveals how AI-driven deep learning models can decode the genetic regulatory switches that define brain cell types across species. By analyzing human, mouse, and chicken brains, researchers found that some brain cell types remain highly conserved over 320 million years, while others have evolved uniquely.This regulatory...

Summary: Environmental factors like stress and medication exposure during pregnancy can shape brain development, but the mechanisms remain unclear. Researchers used brain organoids to study the effects of synthetic glucocorticoids, commonly given to prevent complications in premature births.They found that prolonged exposure led to a shift in neuron types, increasing...