Summary: A single dose of the psychedelic compound 25CN-NBOH significantly improved cognitive flexibility in mice, with effects lasting up to three weeks post-treatment. Treated mice adapted more quickly in rule-switching tasks, indicating enhanced neuroplasticity in the prefrontal cortex.The findings suggest psychedelics may offer lasting cognitive benefits, with potential applications for...
Summary: A new study reveals that while the molecular structure of liver metabolism remains intact during starvation, obesity disrupts the precise timing of metabolic responses. In healthy mice, key “hub” molecules like ATP and AMP responded rapidly and in a coordinated sequence to starvation.In obese mice, this temporal coordination was...
Summary: A large-scale study has found that adolescents who go to bed earlier and get slightly more sleep show better brain function and higher cognitive test performance than their peers. Using wearable devices and brain imaging from over 4,000 participants, researchers discovered that even small differences in sleep duration and...
Summary: A new study shows that combining heavy alcohol use with burn trauma causes severe disruptions in the gut microbiome, leading to inflammation and a weakened gut barrier. Within a day of injury, beneficial bacteria plummet, harmful microbes rise, and levels of butyrate—a key anti-inflammatory compound—drop significantly.This microbial chaos fuels...
Summary: Around 1 in 5 babies are born with a sensitive, unregulated temperament that may raise their risk for anxiety and emotional challenges. A new study shows that contingent responsive parenting—caregivers who accurately respond to a baby’s cues—can reshape early brain activity in ways that support emotional regulation.Infants who received...
